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Table 1 Experimental designs and the results of the Box–Behnken design

From: A green strategy to produce potential substitute resource for bear bile using engineered Saccharomyces cerevisiae

No.

A-Temperature

(°C)

B-Incubation time (h)

C-NADP Na2

(mg)

TUDCA/TCDCA

1

30.00

9.00

0.15

1.28

2

20.00

1.00

0.10

0.36

3

30.00

5.00

0.10

0.94

4

30.00

5.00

0.10

1.09

5

30.00

1.00

0.05

0.33

6

30.00

5.00

0.10

0.88

7

40.00

1.00

0.10

0.34

8

40.00

5.00

0.15

0.72

9

30.00

5.00

0.10

1.02

10

30.00

1.00

0.15

0.48

11

20.00

5.00

0.05

0.74

12

30.00

9.00

0.05

0.86

13

40.00

5.00

0.05

0.35

14

40.00

9.00

0.10

0.38

15

30.00

5.00

0.10

1.12

16

20.00

9.00

0.10

1.22

17

20.00

5.00

0.15

1.14