Table 2 Enzymes and genes envolve in lipid biosynthesis (Campbell and Cronan, 2010; Wang et al. 2021)
From: A comprehensive review on oleaginous bacteria: an alternative source for biodiesel production
S. N | Name of protein/ enzyme | Protein size (active form) | Gene name | Functions |
|---|---|---|---|---|
1 | Acetyl-CoA Carboxylase(ACC) 1.accA Carboxyl- transferase subunit 2.accB Biotin carboxyl carrier protein(BCCP) 3.Biotin carboxylase 4.Carboxyl-transferase subunit | 35 kDa (× 2 with 2AccD) 16.7 kDa (+ biotin × 2) 49.3 kDa(× 2) 33.2 kDa(x2with2 AccA) | accA accB accC accD | Conversion of acetyl-CoA to malonyl-CoA |
2 | Fab D/malonyl-CoA: ACP transacylase | 32.3 kDa (× 1) | fabD gene | Conversion of malonyl-CoA to malonyl-ACP |
3 | FabH /3-ketoacyl-ACP synthase III also called acetoacetyl-ACP synthase | 33.5 kDa (× 2) | FabH | Catalyze 3- ketoacyl-ACP synthase reactions |
4 | FabB /3-Ketoacyl- ACP/synthase I | 42.6 kDa (× 2) | FabB | Catalyze 3- ketoacyl-ACP synthase reactions |
5 | FabF /3-Ketoacyl-ACP synthase II | 43.0 kDa (× 2) | FabF | Catalyze 3- ketoacyl-ACP synthase reactions |
6 | FabG/ an NADPH-dependent 3-ketoacyl-ACP reductase | 25.6 kDa (× 4) | FabG | Conversion of 3ketoacyl-ACP to 3OH acyl ACP |
7 | FabZ / 3-hydroxy acyl-ACP Dehydratase | 16.9 kDa (× 2) | FabZ | Removes H2O from 3OH acyl ACP and forms enoyl—ACP |
8 | FabI / an enoyl-ACP reductase | 27.7 kDa (× 4) | FabI | Reduction of enoyl ACP to acyl ACP |