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Fig. 1 | Bioresources and Bioprocessing

Fig. 1

From: Excellent removal of knob-into-hole bispecific antibody byproducts and impurities in a single-capture chromatography

Fig. 1

Schematic representation of the model asymmetric bsAbs along with their possible major byproducts. FabscFv-KiH and Fab2scFv-KiH are the model asymmetric bsAbs used in this study, and their possible major byproducts include the mispaired homodimers and half-antibodies. The corresponding molecular weight indicated below each species was calculated based on its respective protein sequence

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