Table 3 Genes involved in Mn resistance in B. amyloliquefaciens strain Bam1 and B. velezensis strain FZB42

mntR

2,427,694–2,428,122

2,416,837–2,417,265

Mn transport regulator

98.37

mntH

445,942–447,216

464,983–466,257

Mn transport protein; Mn²⁺ absorb pump

95.06

citM

733,033–734,331

773,138–774,436

Mg²⁺/citrate complex secondary transporter; uptake of citrate and Mg²⁺, Co²⁺, Ni²⁺, Mn²⁺

94.00

mneP/ydfM

249,478–250,371

258,470–259,363

Mn²⁺ efflux pump; Mn²⁺ export

98.43

rex

573,425–574,072

–

NADH/NAD sensing repressor that controls expression of cytochrome bd oxidase CydABCD; transcriptional repressor of anaerobically expressed genes involved in anaerobic respiration and fermentation

–

cydA

2,886,171–2,887,565

2,908,508–2,909,904

Cytochromed ubiquinol oxidase subunit I

95.42

cydB

2,887,588–2,888,628

3,703,711–3,704,727

Cytochromed ubiquinol oxidase subunit II

93.76

ctaA

1,466,975–1,467,901

1,474,483–1,475,409

Heme A synthase; heme biosynthesis

95.47

ctaB/cyoE

1,468,245–1,469,162

1,475,753–1,476,670

Protoheme IX farnesyltransferase 2; heme O synthase; heme biosynthesis; Converts heme B (protoheme IX) to heme O

97.39

qoxA

3,688,218–3,689,174

3,647,521–3,648,486

Cytochrome aa3-600 menaquinol oxidase subunit II

98.01

qoxB

3,686,241–3,688,190

3,645,544–3,647,493

Cytochrome aa3-600 menaquinol oxidase subunit I

98.21

qoxC

3,685,612–3,686,226

3,644,915–3,645,529

Cytochrome aa3-600 menaquinol oxidase subunit III

98.70

qoxD

3,685,242–3,685,610

3,644,544–3,644,913

Cytochrome aa3-600 menaquinol oxidase subunit IV

98.37

mhqR

1,356,332–1,356,778

1,305,481–1,305,927

MarR family transcriptional regulator, 2-MHQ and catechol-resistance regulon repressor

96.42

sodA

2,465,696–2,466,301

2,456,118–2,456,723

Fe/Mn superoxide dismutase; a major pool of Mn²⁺ in stationary phase

96.53

mgtE

1,324,228–1,325,583

1,275,422–1,276,777

Primary Mg transporter; Mg uptake; increased expression help to alleviate Mn toxicity

95.28

opuD

2,839,853–2,841,391

2,841,872–2,843,404

Glycine betaine transporter; increased expression can alleviate the Mn toxicity

94.98