Table 1 Recombinant protein expressed in C. reinhardtii chloroplast (the case with the highest expression in each application category)
Protein | Category | Description | Accumulation | References |
|---|---|---|---|---|
VP28 | Antigen | The envelope protein of shrimp white spot syndrome virus (WSSV) | 20.9% TCP | Surzycki et al. 2009 |
HMGB1 | Damage-associated molecular patterns | High mobility group protein 1, mediating damage repair, recruiting innate immune cells and inducing inflammatory cytokine expression | 2.5% TSP | Rasala et al. 2010 |
Pal/Cpl1 | Antimicrobial protein | Endolysin, specifically kills the human pathogen Streptococcus pneumoniae | 1.2% TSP | Stoffels et al. 2017 |
14FN3 | Antibody mimic | Human fibronectin type III (FN3) domain 14 | 3% TSP | Rasala et al. 2010 |
VHH | Nanobody | VHH domains derived from alpacas, acting as an antitoxin to neutralize toxins produced by toxic microorganisms | 4.6% TSP | Barrera et al. 2015 |
M-SAA | Therapeutic protein | Bovine milk isoforms of serum amyloid A, stimulating intestinal epithelial cells to secrete mucin | 5% TSP | Manuell et al. 2007 |
VEGF | Growth factor | Vascular endothelial growth factor, promoting the growth of vascular endothelial cells and inducing vascular proliferation | 2% TSP | Rasala et al. 2010 |
hGh | Protein hormone | Human growth hormone, promoting human growth and development | 0.5Â mg/L culture | Wannathong et al. 2016 |