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Fig. 1 | Bioresources and Bioprocessing

Fig. 1

From: Construction of an Escherichia coli cell factory to synthesize taxadien-5α-ol, the key precursor of anti-cancer drug paclitaxel

Fig. 1

De novo synthesis of oxygenated taxanes in E. coli cell factories. A GC–MS analysis of the products of TaolE1 strain. Seven compounds are taxa‐4(5),11(12)-diene (1), 5(13)-oxa-3(11)-cyclotaxane (iso-OCT, 2), diterpenoid1 (3), 5(12)-oxa-3(11)-cyclotaxane (OCT, 4), taxadiene-5α-ol (5) and other unknown mono-oxygenated diterpenoids (6, 7). B Products concentrations of taxadiene and oxygenated taxanes at 48 h

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