In vitro assessment of multipotential therapeutic importance of Hericium erinaceus mushroom extracts using different solvents

Bioresources and Bioprocessing

Table 5 Detection of maximum non-toxic concentration of the mushroom extracts against Vero cell (cytotoxicity)

ID	Conc. (µg/mL)	Mean OD	Viability %	Toxicity %	SE	CC₅₀
Vero		0.132	100	0	0.009	µg/mL
Ethyl acetate extract	2500	0.014	10.6	89.4	0.003	26
	1250	0.0153	11.6	88.4	0.0003
	625	0.0147	11	89	0.0008
	312.5	0.015	11.3	88.7	0.001
	156.25	0.0167	12.6	87.4	0.0007
	78.12	0.014	10.6	89.4	0.0005
	39.06	0.0293	22.2	77.8	0.0024
	19.53	0.0883	67	33	0.0013
	9.76	0.1037	78.5	21.5	0.0034
	4.88	0.125	99.7	0.3	0.0051
	2.44	0.131	99.8	0.2	0.0015
	1.22	0.134	101.5	0	0.002
Water extract	1280	0.0133	10	90	0.0003	111
	640	0.015	11.4	88.6	0.0021
	320	0.0207	15.7	84.3	0.000882
	160	0.037	28	72	0.002517
	80	0.122	92.4	7.6	0.003606
	40	0.1327	100	0	0.001202
	20	0.133	101	0	0.002186
	10	0.133	101	0	0.000333