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Table 2 Results of CCD ANOVA analysis

From: Combinatorial strategies for production improvement of anti-tuberculosis antibiotics ilamycins E1/E2 from deep sea-derived Streptomyces atratus SCSIO ZH16 ΔilaR

Source

Sum of Squares

df

Mean Square

F-value

p-value

 

Model

37,105.50

9

4122.83

24.50

 < 0.0001

Significant

A

2327.73

1

2327.73

13.83

0.0040

 

B

21,165.21

1

21,165.21

125.79

 < 0.0001

 

C

5567.39

1

5567.39

33.09

0.0002

 

AB

138.09

1

138.09

0.8207

0.3863

 

AC

8.78

1

8.78

0.0522

0.8240

 

BC

375.67

1

375.67

2.23

0.1660

 

A2

2091.52

1

2091.52

12.43

0.0055

 

B2

2323.76

1

2323.76

13.81

0.0040

 

C2

4510.39

1

4510.39

26.81

0.0004

 

Residual

1682.54

10

168.25

   

Lack of fit

1203.06

5

240.61

2.51

0.1678

Not significant

Pure error

479.48

5

95.90

   

Cor total

38,788.04

19