Fig. 5From: Point mutation of V252 in neomycin C epimerase enlarges substrate-binding pocket and improves neomycin B accumulation in Streptomyces fradiaeEffects of NeoN mutant on neomycin production. A Expression of NeoN in E. coli BL21. B Relative enzyme activities in NeoN mutants. C Production of neomycin B and neomycin C by strain SF-2-NeoNV252A during fermentationBack to article page