Fig. 2From: Transcription regulation strategies in methylotrophs: progress and challengesTranscription regulation mechanism of CRISPR-based strategies. A Regulation mechanism of CRISPRi: inhibit transcription process by blocking RNA polymerase; B Regulation mechanism of CRISPRi: repress the transcription of target genes by handling a repressor; C Regulation mechanism of CRISPRa: activate the transcription of target genes by handling an activatorBack to article page