Transcription regulation strategies in methylotrophs: progress and challenges

Bioresources and Bioprocessing

Table 1 The intensity of different reported promoters in Methylotrophic bacteria

Promoter	Gene product	Condition	Strength	Host	References
P_tac		Methane	Strong	M. buryatense 5GB1	(Puri et al. 2015)
P_rpoD	Sigma 70 factor RpoD	Methane	Weak	M. buryatense 5GB1
P_lac		Methane	Weak	M. buryatense 5GB1
P_mxaF	Methanol dehydrogenase	Methane	Strong	M. buryatense 5GB1
P_mxaF	Methanol dehydrogenase	Methane	Weak	M. trichosporium OB3b	(Lee et al. 2021)
P_J23101		Methane	Weak	M. buryatense 5GB1	(Wilson et al. 2021)
P_J23112		Methane	Inactive	M. buryatense 5GB1
P_J23117		Methane	Inactive	M. buryatense 5GB1
P_J23119		Methane	Strong	M. buryatense 5GB1
P_CT5		Methane	Strong	M. buryatense 5GB1	(Garg et al. 2018a)
P_sMMO	Soluble methane monooxygenase	Methane	Strong	M. silvestris BL2	(Smirnova et al. 2018)
		Methanol	Weak	M. silvestris BL2	(Smirnova et al. 2018)
		Acetate	Inactive	M. silvestris BL2	(Theisen et al. 2005)
P_ectA	Ectoine	Low salinity	Weak	M. alcaliphilum 20Z	(Mustakhimov et al. 2010)
P_ectA	Ectoine	High salinity	Strong	M. alcaliphilum 20Z	(Mustakhimov et al. 2010)
P_tal	Transaldolase		Strong	Methylomonas sp. DH-1	(Lee et al. 2021)
P_DnaA	Chromosomal replication initiator protein		Weak	Methylomonas sp. DH-1
P_Integrase	Integrase		Weak	Methylomonas sp. DH-1
P_rpmB	50S ribosomal protein L28		Weak	Methylomonas sp. DH-1
P_hps	Hexulose 6-phosphate synthase	Methane	Strong	Methylomonas sp. strain 16a	(Ye et al. 2007)