Fig. 8From: Engineering a norcoclaurine synthase for one-step synthesis of (S)-1-aryl-tetrahydroisoquinolinesStructural analysis of the substrate-binding pocket of TfNCS and its mutant L68T/M97V using POCASA 1.1. A Sectional view of the substrate pocket in TfNCS. B Sectional view of the substrate pocket in mutant L68T/M97V modelled by AlphaFold2. C Volume of the substrate-binding pocket in the WT enzyme. D Volume of the substrate-binding pocket in mutant L68T/M97VBack to article page