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Table 4 Di- and tri-peptides derived from P. esculenta with estimated IC 50 less than 50 μM

From: Virtual screening for angiotensin I-converting enzyme inhibitory peptides from Phascolosoma esculenta

Peptide Estimated IC50 Peptide Estimated IC50 Peptide Estimated IC50
WNF 0.12 YIF 13.1 DSL 27.9
HKF 0.42 RPF 13.3 IR 28.9
WCF 0.47 APF 13.4 TGF 29.5
WPF 0.85 REL 13.7 NWL 30.7
WWF 1.18 YK 13.9 FFK 30.9
YVR 1.45 AEF 14.1 GYF 32.2
NRF 1.71 AYF 14.7 ISF 32.3
TYF 1.75 KTL 14.8 FK 33.2
IHR 2.06 WGK 14.9 SPF 33.4
WML 2.15 DWL 14.9 VML 33.7
WAF 3.27 SSF 15.0 KPL 36.1
IWL 5.22 NSF 15.4 ISL 36.5
RSF 5.44 VKL 16.1 QF 36.7
IRF 5.72 MAL 16.3 TML 36.9
CVF 7.15 NR 17.0 QEL 37.0
YIK 7.33 MTL 17.1 MKF 38.0
MGF 7.38 IMF 17.5 YAL 38.6
YF 7.48 WR 17.7 EEF 40.4
KRF 8.11 ER 18.1 IGR 40.5
SR 9.05 AEL 19.4 TEF 41.1
GNL 9.09 QDF 19.5 TTK 41.6
GKF 9.51 YTL 19.7 SGF 41.6
WTR 10.2 PIL 19.9 KVF 42.0
PRL 10.2 KDL 20.2 SIL 43.0
SYL 10.4 SVF 20.8 EVL 43.7
WF 10.6 YSK 21.5 DMF 46.6
IIL 10.8 VVF 22.5 RTL 46.9
WAL 11.3 ITK 22.6 QAL 47.0
AQF 11.5 DR 23.4 TPF 47.0
RAL 11.8 WQK 23.9 HSL 47.1
PGF 12.2 PKL 24.9 NAL 47.1
NVL 12.7 EIF 25.2 SHL 48.0
HTL 13.1 VGF 27.8 STF 49.4