Skip to main content

Ferulic acid production by metabolically engineered Escherichia coli

Ferulic acid (p-hydroxy-3-methoxycinnamic acid, FA) is a natural substance present in plant cell walls, with antioxidant and anticancer properties. It is widely used in medicine etc. Extracting FA through alkaline hydrolysis of plant is the main approach for the commercial FA production. However, such process is costly. Here, a heterologous FA producing E. coli was constructed by introducing several genes from Rhodobactor sp., Saccharothrix sp., and Triticum sp. Moreover, E. coli native pntAB (for NADPH overproduction) and a non-native methionine kinase (MetK from Streptomyces sp.) were overexpressed, which resulted in the highest FA production (212 mg/L) by flask fermentation.

Read the full article here


Aims and scope

Bioresources and Bioprocessing (BIOB) is a peer-reviewed open access journal published under the brand SpringerOpen. BIOB aims at providing an international academic platform for exchanging views on and promoting research to support bioresource development, processing and utilization in a sustainable manner. As an application-oriented research journal, BIOB covers not only the application and management of bioresource technology but also the design and development of bioprocesses that will lead to new and sustainable production processes.

BIOB publishes original and review articles on most topics relating to bioresource and bioprocess engineering, including:

  • Biochemical and microbiological engineering
  • Biocatalysis and biotransformation
  • Biosynthesis and metabolic engineering
  • Bioprocess and biosystems engineering
  • Bioenergy and biorefinery
  • Cell culture and biomedical engineering
  • Food, agricultural and marine biotechnology
  • Bioseparation and biopurification engineering
  • Bioremediation and environmental biotechnology

Recent News

Call for Papers : Special Issue on Bioresources and Bioprocessing

Call for Papers

BioenergyA Sustainable Solution for Carbon Neutrality

A Special Issue of Bioresources and Bioprocessing for

WBS2021: The 12th International Bioenergy Symposium


Guest Editors: Dehua Liu, Xuebing Zhao, Wei Du, Zhen Chen

Bioresources and Bioprocessing (BIOB) plans to publish a Special Issue with the subject of “BioenergyA Sustainable Solution for Carbon Neutrality”. This special issue is in liaison with the 12th International Bioenergy Symposium (WBS2021,, which will be held in Nanning, China during 19–21 November 2021. All the participants of this exciting symposium are cordially invited to submit their original research articles including rapid communications or mini-reviews to this open-access but free-of-charge journal which is published by the Springer Nature group and sponsored by the State Key Laboratory of Bioreactor Engineering (China). The Impact Factor of this China-based and SCI-indexed biotechnology journal is rapidly increasing, with an Impact Factor of 4.578 as of 2020.

Both reviews and research articles are welcome. The topics of interest include, but are not limited to:

  • Status and prospect of biofuels
  • Policy and market of biofuels
  • Fuel ethanol technology (1st and 2nd generation)
  • Systems biology and metabolic engineering for biofuels and biomass-based chemicals
  • Metabolic modeling and simulation for biofuels and biomass based chemicals
  • Biodiesel technology
  • Pretreatment and bioconversion of biomass
  • Biobased polymers and materials
  • Biorefining technology
  • LCA of biofuels

All papers and supplementary information (if any) should be submitted online ( and prepared according to the BIOB guidelines ( Authors should indicate that the paper is submitted for the special issue in their cover letter and is not published or being considered to publish elsewhere. All submissions will be subject to peer review before possible acceptance for publication in BIOB which is now free of charge and highly accessed/cited by readers from all over the world.

The date open for submission to the WBS2021 Special Issue: From Now On;

Until the deadline: December 15, 2021.

Affiliated with

Annual Journal Metrics

  • Speed
    40 days to first decision for reviewed manuscripts only
    36 days to first decision for all manuscripts
    105 days from submission to acceptance
    10 days from acceptance to publication

    Citation impact
    4.578 - 2-year Impact Factor
    1.746 - Source Normalized Impact per Paper (SNIP)
    1.053 - SCImago Journal Rank (SJR)

    15 Altmetric mentions

This journal is indexed by

    • SCOPUS
    • Science Citation Index Expanded 
    • Google Scholar
    • CNKI
    • DOAJ
    • EBSCO Discovery Service
    • EBSCO TOC Premier
    • OCLC WorldCat Discovery Service
    • ProQuest Biological Science Database
    • ProQuest Materials Science & Engineering Database
    • ProQuest Natural Science Collection
    • ProQuest SciTech Premium Collection
    • ProQuest Technology Collection
    • ProQuest-ExLibris Primo
    • ProQuest-ExLibris Summon