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Ferulic acid production by metabolically engineered Escherichia coli

Ferulic acid (p-hydroxy-3-methoxycinnamic acid, FA) is a natural substance present in plant cell walls, with antioxidant and anticancer properties. It is widely used in medicine etc. Extracting FA through alkaline hydrolysis of plant is the main approach for the commercial FA production. However, such process is costly. Here, a heterologous FA producing E. coli was constructed by introducing several genes from Rhodobactor sp., Saccharothrix sp., and Triticum sp. Moreover, E. coli native pntAB (for NADPH overproduction) and a non-native methionine kinase (MetK from Streptomyces sp.) were overexpressed, which resulted in the highest FA production (212 mg/L) by flask fermentation.

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Bioresources and Bioprocessing (BIOB) is a peer-reviewed open access journal published under the brand SpringerOpen. BIOB aims at providing an international academic platform for exchanging views on and promoting research to support bioresource development, processing and utilization in a sustainable manner. As an application-oriented research journal, BIOB covers not only the application and management of bioresource technology but also the design and development of bioprocesses that will lead to new and sustainable production processes.

BIOB publishes original and review articles on most topics relating to bioresource and bioprocess engineering, including:

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Call for Papers : Special Issue on Bioresources and Bioprocessing

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BioenergyA Sustainable Solution for Carbon Neutrality

A Special Issue of Bioresources and Bioprocessing for

WBS2021: The 12th International Bioenergy Symposium

(http://wbs2021.csp.escience.cn)

Guest Editors: Dehua Liu, Xuebing Zhao, Wei Du, Zhen Chen

Bioresources and Bioprocessing (BIOB) plans to publish a Special Issue with the subject of “BioenergyA Sustainable Solution for Carbon Neutrality”. This special issue is in liaison with the 12th International Bioenergy Symposium (WBS2021, http://wbs2021.csp.escience.cn), which will be held in Nanning, China during 19–21 November 2021. All the participants of this exciting symposium are cordially invited to submit their original research articles including rapid communications or mini-reviews to this open-access but free-of-charge journal which is published by the Springer Nature group and sponsored by the State Key Laboratory of Bioreactor Engineering (China). The Impact Factor of this China-based and SCI-indexed biotechnology journal is rapidly increasing, with an Impact Factor of 4.578 as of 2020.

Both reviews and research articles are welcome. The topics of interest include, but are not limited to:

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The date open for submission to the WBS2021 Special Issue: From Now On;

Until the deadline: December 15, 2021.

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