Tuning a bi-enzymatic cascade reaction in Escherichia coli to facilitate NADPH regeneration for ε-caprolactone production
ε-Caprolactone is a monomer of poly(ε-caprolactone) which has been widely used in tissue engineering due to its biodegradability and biocompatibility. To meet the massive demand for this monomer, an efficient whole-cell biocatalytic approach was constructed to boost the ε-caprolactone production using cyclohexanol as substrate. Combining an alcohol dehydrogenase (ADH) with a cyclohexanone monooxygenase (CHMO) in Escherichia coli, a self-sufficient NADPH-cofactor regeneration system was obtained. The engineered whole-cell biocatalyst was used in four sequential batches to achieve a production of 126 mM ε-caprolactone with a high molar yield of 0.78 mol/mol.
Read the full article hereArticles
-
-
Real-time and on-line monitoring of ethanol fermentation process by viable cell sensor and electronic nose
-
Inhibitory effect of low-molecular-weight peptides (0–3 kDa) from Spirulina platensis on H2O2-induced oxidative damage in L02 human liver cells
-
Pulp and paper mill wastes: utilizations and prospects for high value-added biomaterials
-
Locally available agroresidues as potential sorbents: modelling, column studies and scale-up
-
Bigdata analytics identifies metabolic inhibitors and promoters for productivity improvement and optimization of monoclonal antibody (mAb) production process
-
Anti-oxidant and anti-hyperlipidemic effects of cordycepin-rich Cordyceps militaris in a Sprague–Dawley rat model of alcohol-induced hyperlipidemia and oxidative stress
-
Leaf extract mediated green synthesis of silver nanoparticles from widely available Indian plants: synthesis, characterization, antimicrobial property and toxicity analysis
-
Agro-industrial wastes and their utilization using solid state fermentation: a review
-
Current status of cow dung as a bioresource for sustainable development
Aims and scope
Bioresources and Bioprocessing (BIOB) is a peer-reviewed open access journal published under the brand SpringerOpen. BIOB aims at providing an international academic platform for exchanging views on and promoting research to support bioresource development, processing and utilization in a sustainable manner. As an application-oriented research journal, BIOB covers not only the application and management of bioresource technology but also the design and development of bioprocesses that will lead to new and sustainable production processes.
BIOB publishes original and review articles on most topics relating to bioresource and bioprocess engineering, including:
- Biochemical and microbiological engineering
- Biocatalysis and biotransformation
- Biosynthesis and metabolic engineering
- Bioprocess and biosystems engineering
- Bioenergy and biorefinery
- Cell culture and biomedical engineering
- Food, agricultural and marine biotechnology
- Bioseparation and biopurification engineering
- Bioremediation and environmental biotechnology
Recent News
Affiliated with
Bioresources and Bioprocessing is associated with the State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology.
Annual Journal Metrics
-
Speed
40 days to first decision for reviewed manuscripts only
36 days to first decision for all manuscripts
105 days from submission to acceptance
10 days from acceptance to publicationCitation impact
1.295 - Source Normalized Impact per Paper (SNIP)
0.860 - SCImago Journal Rank (SJR)
5.60- CiteScoreUsage
518,539 downloads
15 Altmetric mentions
- ISSN: 2197-4365 (electronic)
This journal is indexed by
-
- SCOPUS
- Emerging Sources Citation Index
- Google Scholar
- CNKI
- DOAJ
- EBSCO Discovery Service
- EBSCO TOC Premier
- OCLC WorldCat Discovery Service
- ProQuest Biological Science Database
- ProQuest Materials Science & Engineering Database
- ProQuest Natural Science Collection
- ProQuest SciTech Premium Collection
- ProQuest Technology Collection
- ProQuest-ExLibris Primo
- ProQuest-ExLibris Summon