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Featured article: A robust tool for yeast genome editing was developed by Chinese scientists

New Content ItemA robust genome editing tool was successfully developed by Chinese scientists for integrating artificially designed DNA parts into Saccharomyces cerevisiae, which is one of the most important industrial microorganisms. The feasibility of scCRISPR/Cpf1 for yeast cell factory development was validated by creating a patchoulol producing strain through two rounds of iterative genomic integration.
As a result, scCRISPR/Cpf1 enables singleplex and tripleplex genomic integration of in vivo assembled DNA parts with 80% and 32% efficiencies, respectively. Furthermore, the patchoulol production strain was rapidly engineered and optimized through two rounds of iterative genomic integration using scCRISPR/Cpf1. Therefore, scCRISPR/Cpf1 facilitates the genome editing of Saccharomyces cerevisiae by circumventing the step to clone a site-specific crRNA plasmid, which enriches the current set of tools for yeast strain engineering.

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Power the Future with Biomass
Deadline for submissions: 31st Aug. 2018



Aims and scope

Bioresources and Bioprocessing (BIOB) is a peer-reviewed open access journal published under the brand SpringerOpen. BIOB aims at providing an international academic platform for exchanging views on and promoting research to support bioresource development, processing and utilization in a sustainable manner. As an application-oriented research journal, BIOB covers not only the application and management of bioresource technology but also the design and development of bioprocesses that will lead to new and sustainable production processes.

BIOB publishes original and review articles on most topics relating to bioresource and bioprocess engineering, including:

  • Biochemical and microbiological engineering
  • Biocatalysis and biotransformation
  • Biosynthesis and metabolic engineering
  • Bioprocess and biosystems engineering
  • Bioenergy and biorefinery
  • Cell culture and biomedical engineering
  • Food, agricultural and marine biotechnology
  • Bioseparation and biopurification engineering
  • Bioremediation and environmental biotechnology

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