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Highly efficient production of an influenza H9N2 vaccine using MDCK suspension cells

The use of H9N2 subtype avian influenza vaccines is an effective approach for the control of the virus spread among the poultry. The cell culture-based production platform may overcome the limitations of conventional egg-based platform. The development of serum-free suspension cell culture allows even higher virus productivity. Dr. Xuping Liu and his coworkers at East China University of Science and Technology demonstrated the promising application of an adherent Mardin–Darby canine kidney (MDCK) cell line by adapting it to the suspension growth in a serum-free medium for highly efficient production of the influenza H9N2 vaccine.  

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Call for Papers

Biochemical engineering: perspectives in the golden age of bioeconomy

A special issue in memory of Prof. Daniel I. C. Wang for his excellent contributions and achievements in the field of biochemical and biological engineering.

Submission deadline: Apr. 30, 2021


Aims and scope

Bioresources and Bioprocessing (BIOB) is a peer-reviewed open access journal published under the brand SpringerOpen. BIOB aims at providing an international academic platform for exchanging views on and promoting research to support bioresource development, processing and utilization in a sustainable manner. As an application-oriented research journal, BIOB covers not only the application and management of bioresource technology but also the design and development of bioprocesses that will lead to new and sustainable production processes.

BIOB publishes original and review articles on most topics relating to bioresource and bioprocess engineering, including:

  • Biochemical and microbiological engineering
  • Biocatalysis and biotransformation
  • Biosynthesis and metabolic engineering
  • Bioprocess and biosystems engineering
  • Bioenergy and biorefinery
  • Cell culture and biomedical engineering
  • Food, agricultural and marine biotechnology
  • Bioseparation and biopurification engineering
  • Bioremediation and environmental biotechnology

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This journal is indexed by

    • SCOPUS
    • Emerging Sources Citation Index
    • Google Scholar
    • CNKI
    • DOAJ
    • EBSCO Discovery Service
    • EBSCO TOC Premier
    • OCLC WorldCat Discovery Service
    • ProQuest Biological Science Database
    • ProQuest Materials Science & Engineering Database
    • ProQuest Natural Science Collection
    • ProQuest SciTech Premium Collection
    • ProQuest Technology Collection
    • ProQuest-ExLibris Primo
    • ProQuest-ExLibris Summon