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Efficient production of butyl butyrate from glucose by a cognate E. coli consortium


Butyl butyrate (BB) is important in industry as a source of flavor/fragrance and as a solvent. BB can be produced by esterification of butyrate and butanol. Some Clostridium spp. can produce butyrate into butanol, but most of the butyrate produced by acetone-butanol- ethanol (ABE) fermentation is converted to butanol, resulting in the insufficient butyrate available for the esterification reaction. This problem could be overcome by considering a cognate microbial consortium, consisting of two engineered butyrate- and butanol- producing E. coli strains with nearly identical genetic background. This allows the efficient BB production with the highest titer and yield.


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Bioresources and Bioprocessing (BIOB) is a peer-reviewed open access journal published under the brand SpringerOpen. BIOB aims at providing an international academic platform for exchanging views on and promoting research to support bioresource development, processing and utilization in a sustainable manner. As an application-oriented research journal, BIOB covers not only the application and management of bioresource technology but also the design and development of bioprocesses that will lead to new and sustainable production processes.

BIOB publishes original and review articles on most topics relating to bioresource and bioprocess engineering, including:

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