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Bioresources and Bioprocessing
Fig. 4 | Bioresources and Bioprocessing

Fig. 4

From: Combined 13C-assisted metabolomics and metabolic flux analysis reveals the impacts of glutamate on the central metabolism of high β-galactosidase-producing Pichia pastoris

Fig. 4

Possible modulation mechanism of glutamate on the central metabolism of P. pastoris G1HL. Red solid lines up-regulated fluxes, green solid lines down-regulated fluxes. Red metabolite names metabolites with increased pool sizes, green metabolite names metabolites with decreased pool sizes. Red dotted lines positive regulations, green dotted lines negative regulations. (GPI glucose-6-phosphate isomerase; IDH isocitrate dehydrogenase; OGDC α-ketoglutaric dehydrogenase)

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