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Table 3 Matrix of independent variables in coded and actual values with their corresponding responses

From: Development of an economical fermentation platform for enhanced ansamitocin P-3 production in Actinosynnema pretiosum

Run

Cane molasses

Glycerol

Soybean powder

AP-3 (mg/L)

Experimental production

Predicted production

1

0

1

− 1

95.8 ± 1.1

94.5

2

1

0

1

93.0 ± 0.1

97.2

3

1

0

− 1

85.1 ± 3.0

84.4

4

− 1

0

− 1

96.6 ± 4.9

92.3

5

0

0

0

99.6 ± 8.9

99.7

6

0

0

0

93.4 ± 2.6

99.7

7

0

− 1

− 1

83.8 ± 4.5

90.0

8

0

0

0

91.3 ± 7.9

99.7

9

− 1

1

0

79.1 ± 3.1

84.6

10

0

0

0

109.8 ± 3.2

99.7

11

− 1

− 1

0

76.1 ± 1.0

74.1

12

0

0

0

104.4 ± 0.4

99.7

13

0

− 1

1

75.8 ± 1.2

77.1

14

1

1

0

94.5 ± 5.5

96.5

15

− 1

0

1

57.4 ± 4.3

58.1

16

1

− 1

0

99.0 ± 6.4

93.5

17

0

1

1

92.2 ± 5.8

86.0