Optimization of immobilized Lactobacillus pentosus cell fermentation for lactic acid production

Bioresources and Bioprocessing

Table 3 Experimental data of LA production by immobilized L. pentosus ATCC 8041 cells

Run	Factor				Response
Run	Bead diameter D_B (mm)	pH	Initial glucose concentration C_G (g/L)	Biomass B_W, CDW (mg)	LA yield Y_LA (g/g)	LA productivity P_LA g/(L × h)
1	3	5	110	200	0.894 ± 0.006	1.903 ± 0.013
2	2	5	110	300	0.916 ± 0.004	2.004 ± 0.009
3	3	5	100	300	0.907 ± 0.003	1.838 ± 0.007
4	4	6	110	400	0.919 ± 0.002	1.891 ± 0.007
5	3	6	120	400	0.922 ± 0.006	2.210 ± 0.014
6	4	6	100	300	0.924 ± 0.002	1.828 ± 0.006
7	3	6	110	300	0.930 ± 0.001	2.090 ± 0.003
8	3	6	100	400	0.911 ± 0.003	1.720 ± 0.006
9	4	6	120	300	0.908 ± 0.005	2.117 ± 0.012
10	3	5	110	400	0.917 ± 0.006	1.965 ± 0.014
11	3	6	100	200	0.942 ± 0.002	1.972 ± 0.007
12	2	6	110	400	0.934 ± 0.004	2.071 ± 0.009
13	3	6	110	300	0.935 ± 0.001	2.101 ± 0.004
14	3	6	110	300	0.932 ± 0.003	2.049 ± 0.007
15	3	7	120	300	0.871 ± 0.008	1.975 ± 0.016
16	2	6	100	300	0.937 ± 0.002	1.911 ± 0.006
17	3	7	100	300	0.893 ± 0.006	1.756 ± 0.012
18	3	5	120	300	0.897 ± 0.005	2.059 ± 0.012
19	3	6	110	300	0.933 ± 0.002	2.096 ± 0.005
20	2	7	110	300	0.892 ± 0.004	1.891 ± 0.009
21	3	7	110	400	0.866 ± 0.007	1.782 ± 0.014
22	4	5	110	300	0.902 ± 0.003	1.914 ± 0.006
23	2	6	120	300	0.917 ± 0.001	2.202 ± 0.005
24	4	7	110	300	0.883 ± 0.005	1.815 ± 0.010
25	3	6	110	300	0.931 ± 0.003	2.092 ± 0.007
26	3	6	120	200	0.903 ± 0.007	1.987 ± 0.016
27	3	7	110	200	0.894 ± 0.003	1.902 ± 0.006
28	2	6	110	200	0.928 ± 0.002	1.972 ± 0.004
29	4	6	110	200	0.919 ± 0.005	2.025 ± 0.011