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Bioresources and Bioprocessing
Fig. 4 | Bioresources and Bioprocessing

Fig. 4

From: Chitopentaose inhibits hepatocellular carcinoma by inducing mitochondrial mediated apoptosis and suppressing protective autophagy

Fig. 4

(GlcN)5 induced mitochondrial-mediated apoptosis in HepG2 cells. A Detection of bax and bcl-2 levels by qPCR. B Detection of mitochondrial membrane potential by JC-1 analysis. C Detection of cytoplasmic cytochrome c by western blot. D Detection of Bax, Bcl-2, cleaved Caspase-3, cleaved Caspase-9, and Cleaved PARP levels by western blot. Cells were treated with different concentration of (GlcN)5. Data were represented as mean ± SD Significance between groups was marked by various letters, a, b, c, etc. (One-way ANOVA)

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