Fig. 3
From: Multi-omics analysis defines 5-fluorouracil drug resistance in 3D HeLa carcinoma cell model
The effect of 5-FU on 3D MTSs. a Cytotoxicity assay. b Cell apoptosis and cell cycle. c Mitochondrial respiration profile. d ROS measurement. The measured concentrations of extracellular e glucose, f glutamine, g ammonium and h lactate. Omy, oligomycin; Rot, rotenone; Ama, antimycin A. The culture time of 2D monolayer culture and 3D MTS was shown on the bottom and top axis, respectively