Fig. 9From: Structure-guided engineering of a flavin-containing monooxygenase for the efficient production of indirubina Titer of indirubin in vivo of various mutants. b Fed-batch fermentation profiles of the engineered strain W3. Indirubin titer, cell growth and glucose concentration are shown. The data shown were chosen as a typical result from a series of experiments with consistent results. Error bar indicate standard error of the mean. c 5 L bioreactor used for fed-batch fermentation of the W3 strainBack to article page