Fig. 5From: Laccase-catalyzed lignin depolymerization in deep eutectic solvents: challenges and prospectsIllustration of the distribution of water around an enzyme (e.g., laccase) in a DES environment. Poor water-soluble substrate (like lignin) is efficiently dissolved in bulk DES. The space around the laccase can be distributed into two different regions: (1) an enzyme vicinity region, where the interaction of water with the laccase is dominant, and (2) a bulk DES phase region, where the interaction of water with the DES mixture dominates. Essential water layer might dwindle or disappear due to water stripping by hydrophilic DESBack to article page