Fig. 4
From: Efficient production of salvianic acid A from l-dihydroxyphenylalanine through a tri-enzyme cascade
Crystal structure and catalytic mechanism of LaPPR. a X-ray crystal structure and electron density map of apo-LaPPR. b Docking binding model of NADH and DHPPA into the active site of LaPPR. c The catalytic mechanism of LaPPR. Hydrogen bonds are shown in gold dashed lines. d Alanine scanning of key residues. Asterisks indicate that the activity was not measurable. The data represent mean ± s.d., as determined from three independent experiments