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Bioresources and Bioprocessing
Fig. 4 | Bioresources and Bioprocessing

Fig. 4

From: Reconstruction the feedback regulation of amino acid metabolism to develop a non-auxotrophic l-threonine producing Corynebacterium glutamicum

Fig. 4

Replacing the native CgdapA gene with SpdapA in ZcglT3 to reduce the by-product l-lysine. The 24-deep-well plate fermentation was performed at 30 °C for 24 h. ZcglT4, ZcglT3 derivative with replacement of the native CgdapA with SpdapA. Thr, l-threonine; Lys, l-lysine; Ile, l-isoleucine; Gly, glycine; Hse, l-homoserine. Data are presented as mean values +/− SD (n = 3 independent experiments). ***P < 0.001, student’s two-tailed t-test

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