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Call for Papers:

Beyond Natural Enzymes: The Power of Directed Evolution

 A special issue of Bioresources and Bioprocessing, dedicated to Prof. Manfred T. Reetz for his pioneering contributions and achievements in the field of directed evolution and protein engineering.

 Guest Editors: Aitao Li, Jianbo Wang, Zhoutong Sun, Gao-Wei Zheng and Guangyue Li

Bioresources and Bioprocessing (BIOB) plans to publish a special issue with the subject of “Beyond natural enzymes: the power of directed evolution”, dedicated to Prof. Manfred T. Reetz for his pioneering contributions and achievements in the field of directed evolution and protein engineering. The field of enzyme biotechnology is undergoing rapid changes and biotechnology requires enzymes which are functional and stable under a wide range of unnatural conditions. Even more desirable would be enzymes are capable of performing non-natural reactions that have never been seen in nature before. However, the natural enzymes do not always meet the requirements in a given process, therefore, directed evolution has been employed to bridge the gap between natural enzymes and commercial applications. Here, we are seeking contributions from the directed evolution and protein engineering community, in the forms of either original articles or review articles, to this open-access and free-of-charge journal which is published by Springer Nature group and sponsored by the State Key Laboratory of Bioreactor Engineering, China. This five-year old journal has been included in famous databases such as SCOPUS (Elsevier) and ESCI (Clarivate). More importantly, to save your valuable time, the peer-review process will be started immediately after the manuscript is submitted to BIOB and each of the accepted papers will be published quickly within 3-5 days in one-by-one mode.

The topics of interest include (but not limited to) the topics listed below:

  • Enzyme/protein engineering
  • Methodology development in mutagenesis methods
  • Methodology development in screening/selection methods
  • Combined directed evolution and computational design in enzyme engineering
  • Use of directed evolution in metabolic engineering
  • Use of directed evolution in synthetic biotechnology
  • Use of directed evolution in biorefinery and biomass utilization
  • Overview and perspectives of directed evolution on certain class of enzymes
  • Other topics related to directed enzyme evolution

All papers and supplementary information (if any) should be submitted online ( and prepared according to the BIOB guidelines ( Authors should indicate that the paper is submitted for the special issue in their cover letter and is not published or being considered to publish elsewhere. All submissions will be subjected to peer review as regularly before possible acceptance for publication in BIOB which is free of charge and highly accessed by readers from all over the world.

The Special IssueBeyond natural enzymes: The power of directed evolution" is open for submission now.

The deadline: Mar 31, 2020.

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